RABEPRAZOLE SULFIDE

PubChem: Introduction

Chemical Name:Rabeprazole Sulfide

CAS.NO:117977-21-6

Synonyms:Rabeprazole Sulfide

2-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methylthio]benzimidazole

2-[[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl ]methyl]thio]-1H-benzimidazole

2-[[[4-(3-Methoxy Propoxy)-3-methyl pyridine-2-yl ]methyl ] thio]-1H-benzimidazole

2-(((4-(3-METHOXYPROPOXY)-3-METHYL-2-PYRIDINYL)METHYL)THIO)-1H-BENZIMIDAZOLE

2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfanyl]-1H-benzimidazole

Physical and Chemical Properties:

Density 1.3±0.1 g/cm3

Boiling Point 546.4±60.0 °C at 760 mmHg

Melting Point 120.5-121.5ºC

Molecular Formula C18H21N3O2S

Molecular Weight 343.443

Flash Point 284.2±32.9 °C

Specification:

Appearance:White to off-white crystalline powder

Assay(HPLC):≥98.0%

Packing:25 kg/drum, can also be packaged according to customer requirements

Storage:Store in a cool, ventilated place

Application:Intermediates of Rabeprazole(CAS:117976-89-3).

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Internet Archives

Archives from internet relating to this product

RABEPRAZOLE SODIUM « New Drug Approvals: Oct 24 2013· The U.S. Pat. No. 5045552 discloses the Rabeprazole and many other substituted benzimidazole-type compounds having anti-ulcer activity. This patent further discloses the process for preparation of Rabeprazole by oxidation of Rabeprazole sulfide using 85% m-chloroperbenzoic acid in a mixture of dichloromethane and diethyl ether followed by work up to get product as oil.

Rabeprazole Related Compound E (25 mg) (2-{[4-(3 ...: benzimidazole) 117977-21-6 Suppliers,provide Rabeprazole Related Compound E (25 mg) (2-{[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methylthio}benzimidazole) 117977-21-6 product and the products related with China (Mainland) Rabeprazole Related Compound E (25 mg) (2-{[4-(3 …,600}

117977-21-6 | Rabeprazole Sulfide | ChemScene llc: ChemScene Provide Rabeprazole Sulfide(CAS 117977-21-6)In-stock or Backordered impuritiesBulk custom synthesisFormular C18H21N3O2SMW 343.44 bulk manufacturing sourcing and procurement.

Rabeprazole: A comprehensive profile - ScienceDirect: Jan 01 2021· The Rabeprazole and many other substituted benzimidazole-style compounds with anti-ulcer activity are reported by Souda et al. .This patent further reveals the method of Rabeprazole preparation using 85% m-chloroperabenzoic acid for oxidation of Rabeprazole sulfide 2 in a mixture of dichloromethane and diethyl ether after that work is performed to get product as oil.

(PDF) Identification and synthesis of potential impurities ...: During the synthesis of bulk drug of rabeprazole sodium we have observed metabolites rabeprazole sulfide and rabeprazole sulfone and related substances rabeprazole-N-oxide rabeprazole sulfone-N ...

Inhibiting Effects of Rabeprazole Sulfide on the Corrosion ...: Rabeprazole sulfide is the commercial name of (2-[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]-methylthio]-1H-benzimidazole). It is a metabolite of an antiulcer drug Rabeprazole. We have investigated the corrosion inhibition effect of this compound on mild steel in 0.5 M H 2 …

Inhibition of mild steel corrosion by Rabeprazole sulfide ...: Jul 01 2012· The inhibition effect of Rabeprazole sulfide (2-[[4-(3-methoxypropoxy)-3-methylpyridine-2-yl]-methylthio]-1H-benzimidazole) (RS) on the corrosion behavior of mild steel in 0.5 M H 2 SO 4 solution was studied by weight loss potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) measurements. Polarization measurements indicate that RS act as a mixed type inhibitor.

Rabeprazole-GLP Pharma Standards: Rabeprazole Sulfide N-Oxide. Rabeprazole Sulfide N-Oxide. Catalogue No : GL-R0105: Common name: Rabeprazole Sulfide N-Oxide: CAS : 924663-40-1: Mol. weight : 359.44: More Info RFQ Request For Quote ×. Rabeprazole Sulfide N-Oxide ...

Rabeprazole thioether | CAS#:117977-21-6 | Chemsrc: Jan 24 2021· Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment[1][2].

Rabeprazole Sulfide N-Oxide - SynZeal: Identification isolation and characterization of new impurity in rabeprazole sodium P. SreenivasaRao Uttam KumarRay P. BadarinadhGupta D.V.N. SrinivasaRao AminulIslam PradeepRajput K.Mukkanti Journal of Pharmaceutical and Biomedical Analysis Volume 52 Issue 4 1 August 2010 Pages 620-624

Rabeprazole Sulfide Impurity | CAS No- 117977-21-6 ...: CAS. No. 117977-21-6. Molecular Formula. C 18 H 21 N 3 O 2 S. Formula Weight. 343.44 g/mol. Synonyms. Rabeprazole USP Related Compound E; Rabeprazole EP Impurity B. Chemical Name.

Rabeprazole N-Alkyl Sulfide - SynZeal: Identification isolation and characterization of new impurity in rabeprazole sodium P. SreenivasaRao Uttam KumarRay P. BadarinadhGupta D.V.N. SrinivasaRao AminulIslam PradeepRajput K.Mukkanti Journal of Pharmaceutical and Biomedical Analysis Volume 52 Issue 4 1 August 2010 Pages 620-624

Rabeprazole Sulfide | C18H21N3O2S | ChemSpider: Rabeprazole Sulfide. More... Validated by Experts Validated by Users Non-Validated Removed by Users. 304S7E320P [DBID] CCRIS 4693 [DBID] PubChem Substance I D 24851494 [DBID] UNII:304S7E320P [DBID] UNII-304S7E320P [DBID] ...

Rabeprazole-d3 Sulfide | C18H21N3O2S - PubChem: Rabeprazole-d3 Sulfide | C18H21N3O2S | CID 46782837 - structure chemical names physical and chemical properties classification patents literature biological ...

Rabeprazole Sulfide CAS 117977-21-6 Watson International ...: Rabeprazole Sulfide Molecular Formula C18H21N3O2S Molecular Weight 343.14 CAS Number (Or Watson Number for Non-CAS Products) 117977-21-6 Use Impurity of API Rabeprazole Links This product is developed by our R&D company Caming Pharmaceutical Ltd (https://www.caming.com/). Quick Inquiry

Rabeprazole Sulfide | CAS 117977-21-6 | SCBT - Santa Cruz ...: Rabeprazole Sulfide is a metabolite of Rabeprazole. References. 1. Miura M. et al. 2006. Eur. J. Clin. Pharmacol. 62: 113-117. PMID: 16389533 2. Sheridan R.P. et al. 2007. J. Med. Chem. 50: 3173-3184. PMID: 17579382 3. Ren S. et al. 2008. Arc. Pharm. Res. 31: 406-413. PMID: 18409057

Rabeprazole Sulfide N-Oxide | C18H21N3O3S - PubChem: Rabeprazole Sulfide N-Oxide. 924663-40-1. 2-[[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-1-ium-2-yl]methylsulfanyl]-1H-benzimidazole. DTXSID30582521Molecular Formula: C18H21N3O3SPubChem CID: 16095900Molecular Weight: 359.4

Rabeprazole Sulfide | Proton Pump Inhibitor | …: Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment.

Rabeprazole Sulfide | Proton Pump Inhibitor | MedChemExpr…: Rabeprazole-d3 Sulfide | C18H21N3O2S | CID 46782837 - structure chemical names physical and chemical properties classification patents literature biological ...Molecular Formula: C18H21N3O2SPubChem CID: 46782837Molecular Weight: 346.5

Rabeprazole Sulfide manufacturer;2-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methylthio]benzimidazole supplier;2-[[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl ]methyl]thio]-1H-benzimidazole factory;2-[[[4-(3-Methoxy Propoxy)-3-methyl pyridine-2-yl ]methyl | ETHYL 2-((5-CHLOROPYRIDIN-2-YL)AMINO)-2-OXOACETATE HYDROCHLORIDE | 2-[2-(2,2,2-TRIFLUOROETHOXY)PHENOXY]ETHYL BROMIDE

Introduction